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What is Promethazine used for?

Doctors usually prescribe Promethazine for the treatment of the symptoms of allergies such as sneezing, runny nose, watery eyes, hives and itching.  Promethazine is an antihistamine and works by reducing the body’s production of histamine which causes these allergies.  Promethazine is also used to prevent the occurrence of motion sickness; as a sleep aid or sedative or to treat some after effects of surgery such as nausea, vomiting or pain.

What are Promethazine side effects?

Patients taking Promethazine can sometimes experience side effects including drowsiness, tinnitus, swollen hands or feet, constipation, dizziness, blurred vision, impotence, anxiety, constipation or weight gain.  Contact your doctor if any of the more serious side effects occur such as seizures; restlessness; balance problems; agitation; bleeding or bruising easily; pale skin; high temperature; palpitations; hallucinations; tremors; twitching; sweating; confusion; tunnel vision; sore throat; jaundice; fainting or decrease in urination. You may develop an allergic reaction to Promethazine and signs of this could include hives; skin rash; trouble breathing or swollen throat, mouth, tongue, lips or face.  You should get medical help immediately if you notice any of these signs after taking Promethazine.

What to know before taking Promethazine?

Do not give Promethazine to children under the age of two as it could cause major problems with breathing or could even be fatal.  If you have conditions such as emphysema or severe asthma or if you are allergic to Phenothiazines, you should not take Promethazine.  Tell your doctor if you have conditions such as liver disease; glaucoma; hypertension; history of seizures; stomach ulcers; kidney disease; heart disease; sleep apnea; urination problems or hypocalcaemia, as you may need to be tested to determine the safest dose.

What is the Promethazine dosage?

Your dose of Promethazine will be prescribed for you by your doctor according to your specific needs.  Do not take larger doses than what has been prescribed for you.  Do not take the medication for longer than the course which your doctor has prescribed. Dosage of Promethazine depends on the condition being treated and the length of the course.  The usual dosage of Promethazine for treating allergies in adults is 10-12.5mg three times each day before eating and once before bed.  Dosage for children over the age of two is usually 5-12.5mg three times each day.  This dosage is dependant on body weight.

What are the Promethazine interactions?

Promethazine has been known to interact with certain medications including Bronchodilators, Tranylcypromine, Solifenacin, Methscopolamine, Guanethidine, Dicyclomine, Selegiline, Dimenhydrinate, Propantheline or Oxybutynin.  It is important to tell your doctor about any other medications you are taking even, pain killers, vitamins or supplements or herbal medications as these could also interact with Promethazine.

What should I avoid while taking Promethazine?

It is advisable to avoid alcohol when taking Promethazine in order to reduce the risk of some side effects.  Promethazine can cause impaired reactions or thoughts so it is advisable to take extra care before taking part in anything which requires full alertness.  As it can cause dizziness, you should be careful to avoid getting up too quickly from lying or sitting.  Promethazine can cause an increased sensitivity to sunlight so you should avoid excessive exposure to the sun or to artificial sun light.

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